Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity relevant to bortezomib, a proteasome inhibitor Employed in the therapy of multiple myeloma. Its synthesis or study is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound in the synthesis of imatinib, a drug that targets precise forms of cancer, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their research is very important for optimizing the output approach and making sure substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is used to treat breast most cancers, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the treatment method of breast cancer. Many intermediates help in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): 7-dihydro-4-oxo-1H-pyrrolo[2 A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, that have numerous programs, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of various gluconic acid derivatives, which might be used in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to Irinotecan hydrochloride trihydrate handle sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).